Tominersen sodium is a second-generation 2′-O- (2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen sodium can be used for the research of Huntington’s disease (HD) [1][2].
Molecular Formula
C230H299N74Na20O122P19S13
Smiles
[Tominersen(sodium)]
Target
Huntingtin
Purity
97.36
Solubility
10 mM in H2O
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
