TP-2

TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs) . TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible[1].

C89H100Cl4N12O8

1607.63

NCCOC1=C(C=CC(C2=CC=[N+](C=C2)CC3=CC=C(C(C4=CC=C(C=C4)C[N+]5=CC=C(C=C5)C6=CC(OCCN)=C(C=C6)OCCN)(C7=CC=C(C=C7)C[N+]8=CC=C(C=C8)C9=CC(OCCN)=C(C=C9)OCCN)C%10=CC=C(C=C%10)C[N+]%11=CC=C(C=C%11)C%12=CC(OCCN)=C(C=C%12)OCCN)C=C3)=C1)OCCN.[Cl-].[Cl-].[Cl-].[Cl-]

Others

10 mM in DMSO

Room temperature