TP-808 [CAS 852821-06-8]

TP-808 is an intermediate used in tetracycline antibiotic synthesis with antimicrobial activity. TP-808 binds to the 30S ribosome subunit of the bacteria, preventing aminoacyl-trNA from entering the A site, thereby inhibiting the extension of the protein chain. TP-808 can be used in antibiotic drug development research[1].

[852821-06-8]

C26H34N2O5Si

482.64

CC(C)(C)[Si](C)(C)O[C@]12[C@](CC=CC2=O)([H])[C@@H](C3=C(C(OCC4=CC=CC=C4)=NO3)C1=O)N(C)C

Bacterial

10mM

99.72

DMSO : 50 mg/mL (ultrasonic)

Store at room temperature 3 years

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335