TPC2-A1-P [CAS 2804595-86-4]

TPC2-A1-P is a powerful and membrane permeable agonist of two pore channel 2 (TPC2) with an EC50 of 10.5 μM. TPC2-A1-P plays its role by mimicking the physiological actions of PI (3,5) P2. TPC2-A1-P also shows higher potency to induce Na2+ mobilisation from TPC2 than TPC-A1-N. TPC2-A1-P can be used to probe different functions of TPC2 channels in intact cells[1][2][3].

[2804595-86-4]

C20H21BrF3NO3

460.28

BrC1=CC(C2=CC(C(O)=O)=C(C)N2CC3CCCCC3)=C(OC(F)(F)F)C=C1

Sodium Channel

99.79

DMSO : 50 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature