Trimebutine (3-TCBS) [CAS 1456509-46-8]

Trimebutine 3-TCBS (GIC-1001) is an innovative formulation designed to release hydrogen sulfide (H2S) in vivo. This compound combines trimebutine with an H2S-releasing antagonist (phenyl 3-thiocarbamate) and exhibits enhanced anti-nociceptive effects in a mouse colonic distension model, superior to conventional trimebutine. GIC-1001 can reduce visceral pain and discomfort associated with lumen distension in a dose-dependent manner, showing potential superiority[1].

[1456509-46-8]

C29H36N2O8S2

604.73

O=C(C1=CC(OC)=C(C(OC)=C1)OC)OCC(N(C)C)(CC)C2=CC=CC=C2.O=S(C3=CC=CC(C(N)=S)=C3)(O)=O

Biochemical Assay Reagents

Room temperature