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Trimidox (hydrochloride) [CAS 95933-75-8]

Trimidox (hydrochloride) [CAS 95933-75-8]

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QM-0104180-01

£90.25 GBP
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Product Details

  • Description

    Trimidox hydrochloride (VF-233) is a ribonucleotide reductase inhibitor with antileukemic activities. Trimidox hydrochloride inhibits the growth of human promyelocytic leukemia HL-60 cells with an IC50 of 35 μM[1].

  • CAS Number

    [95933-75-8]

  • Molecular Formula

    C7H9ClN2O4

  • Molecular Weight

    220.61

  • Smiles

    N=C(C1=CC(O)=C(O)C(O)=C1)NO.Cl

  • Target

    DNA/RNA Synthesis

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H315-H319-H335

  • Precautions

    P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
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Variant Variant total Quantity Price Variant total
1 mgQM-0104180-01
1 mgQM-0104180-01
£90.25/ea		 £0.00
£90.25/ea £0.00
5 mgQM-0104180-02
5 mgQM-0104180-02
£227.39/ea		 £0.00
£227.39/ea £0.00
10 mgQM-0104180-03
10 mgQM-0104180-03
£379.26/ea		 £0.00
£379.26/ea £0.00
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Trimidox (hydrochloride) [CAS 95933-75-8]

Trimidox (hydrochloride) (CAS 95933-75-8) is a certified reference standard supplied by Quantimol for laboratory and scientific research.

Also known as VF-233, Trimidox hydrochloride is a potent ribonucleotide reductase (RNR) inhibitor with antileukemic activity. It inhibits the growth of human promyelocytic leukaemia HL-60 cells with an IC50 of 35 μM. Ribonucleotide reductase is a key enzyme in de novo deoxyribonucleotide synthesis, making RNR inhibitors important tools in cancer biology and antiviral research.

Key properties:

  • Target: Ribonucleotide reductase (RNR)
  • Mechanism: RNR inhibitor
  • CAS Number: 95933-75-8
  • IC50: 35 μM (HL-60 cells)
  • Purity: ≥98% (HPLC)
  • Storage: -20°C, protected from light
  • Solubility: Water or DMSO (recommended)

Applications: Ribonucleotide reductase inhibition, antileukemic research, DNA synthesis studies, cancer cell biology, antiviral drug discovery.

Supplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.