TXB4 is a brain-permeable human monoclonal antibody (mAb) targeting CD71. TXB4 prevents 6-OHDA-induced death of TH-positive neurons in the SNc in a 6-OHDA mouse model of Parkinson's disease (PD) . TXB4 can be used in neurodegenerative diseases, acute brain and spinal cord injury, and depression research[1].
