TY-011 [CAS 1389439-77-3]

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SKU:QM-0082207

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Product Details

Description
TY-011 is an Aurora A/B kinase inhibitor. TY-011 induces abnormal microtubule-kinetochore attachment, leading to DNA damage and apoptosis (Apoptosis) in human gastric cancer cells, and ultimately inhibits cancer cell proliferation, with an IC50 value ranging from 0.11 to 4.49 μM in human gastric cancer cell lines. TY-011 has potential applications in gastric cancer research[1].
CAS Number
[1389439-77-3]
Molecular Formula
C18H16ClN5
Molecular Weight
337.81
Smiles
CC1=C(C(N2)=NN1)N=C(C3=CC=CC=C3Cl)C4=C2C=C(CC)N=C4
Target
Aurora Kinase
Isoform
Aurora A; Aurora B
Shipping Conditions
Room temperature
Hazard Statement
H302-H315-H319-H335
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Variant	Variant total	Quantity	Price	Variant total
1 EachQM-0082207	1 EachQM-0082207 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

TY-011 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.