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Tyk2-IN-22 [CAS 933667-23-3]
Tyk2-IN-22 [CAS 933667-23-3]
SKU:QM-0108134
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Product Details
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Description
Tyk2-IN-22 (Compound A8) is a selective inhibitor for tyrosine kinase 2 (Tyk2), that it inhibits Tyk2, JAK1, and JAK3 with IC50s of 9.7, 148.6, and 883.3 nM, respectively. Tyk2-IN-22 inhibits the downstream STAT5 phosphorylation[1].
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CAS Number
[933667-23-3]
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Molecular Formula
C16H16ClN5O2
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Molecular Weight
345.78
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Smiles
O=C1N2C(NC(C3=CC=C(Cl)C=C3)=N2)=NC(CN4CCOCC4)=C1
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Target
JAK
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Isoform
JAK1; JAK3; Tyk2
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Shipping Conditions
Room temperature
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Tyk2-IN-22 [CAS 933667-23-3]
Tyk2-IN-22 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.