Tyk2-IN-8 [CAS 2704587-24-4]

Tyk2-IN-8 (compound 3) is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1].

[2704587-24-4]

C20H19D3N8O3

425.46

[2H]C([2H])([2H])OC1=C(C2=NN(C)C=N2)C=CC=C1NC3=C(N=NC(NC(C4CC4)=O)=C3)C(NC)=O

Isotope-Labeled Compounds; JAK

98.04

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature