UCI-1

UCI-1 is a SARS-CoV-2 main protease (Mpro) cyclic peptide inhibitor with an IC50 of 160 μM. UCI-1 shows no obvious cytotoxicity at the concentration of inhibiting Mpro. UCI-1 can be used in the study of anti-COVID-19 drugs[1].

C33H45N7O7

651.75

O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(NCCC1=CC=C(CC2=O)C=C1)=O)=O)=O)[C@@H](N2)CC3=CC=CC=C3

SARS-CoV; Virus Protease

Room temperature