UH-NIP-16

UH-NIP-16 exhibits antimicrobial activity against Mycobacterium tuberculosis, with MIC50 of 1.86 and 3.05 μM, for pathogenic mycobacterial strains H37Rv and CDC1551. UH-NIP-16 synergizes with Streptomycin , Isoniazid (HY-B0329), Ethambutol (HY-B0535) and Bedaquiline (HY-14881), potentiates their anti-tuberculosis activities[1].

C17H13ClN4O2

340.76

O=C(N/N=C\C1=CC2=CC(OC)=CC=C2N=C1Cl)C3=CC=NC=C3

Bacterial

10 mM in DMSO

Room temperature