UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM) . UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion[1].
CAS Number
[940290-58-4]
Molecular Formula
C17H13N3O2
Molecular Weight
291.3
Smiles
N=C(C1=CC=C(/C=C2N=C(C3=CC=CC=C3)OC/2=O)C=C1)N
Target
Ser/Thr Protease
Purity
99.85
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)