ULK1-IN-3

ULK1-IN-3 (Compound 8) is a novel chromone-based as a potential inhibitor of ULK1. ULK1-IN-3 inhibits cell cycle, autophagy and induces apoptosis, oxidative stress in colon cancer cell lines[1].

C25H21ClO5

436.88

COC1=CC=C(C(C(C2=CC=C(CCl)C=C2)=C(C3=CC=C(OC)C(OC)=C3)O4)=O)C4=C1

Akt; AMPK; Apoptosis; Autophagy; NF-κB; PARP; Reactive Oxygen Species (ROS) ; ULK

ULK1

Room temperature