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UNC0224 [CAS 1197196-48-7]

UNC0224 [CAS 1197196-48-7]

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SKU:QM-0136493-01

£67.44 GBP
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  • Description

    UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6 nM, an IC50 of 15 nM and a Kd of 23 nM. UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58 nM. UNC0224 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E[1][2].

  • CAS Number

    [1197196-48-7]

  • Molecular Formula

    C26H43N7O2

  • Molecular Weight

    485.67

  • Smiles

    CN1CCC(NC2=C3C=C(OC)C(OCCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1

  • Target

    Histone Methyltransferase

  • Isoform

    EHMT1/GLP/KMT1D; EHMT2/G9a/KMT1C

  • Purity

    98.85

  • Solubility

    DMSO : 16.67 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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1 mgQM-0136493-01
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5 mgQM-0136493-02
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10 mgQM-0136493-03
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50 mgQM-0136493-04
50 mgQM-0136493-04
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100 mgQM-0136493-05
100 mgQM-0136493-05
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UNC0224 [CAS 1197196-48-7]

UNC0224 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.