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UNC3474 [CAS 1648707-79-2]

UNC3474 [CAS 1648707-79-2]

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SKU:QM-0152163-01

£250.47 GBP
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  • Description

    UNC3474 is a small molecule ligand, binding with 53BP1. UNC3474 binds the aromatic methyl-lysine binding cage of 53BP1TT, with a dissociation constant (Kd) of 1.0 ± 0.3 μM. UNC3474 inhibits the recruitment of 53BP1 to DSBs by stabilizing a pre-existing autoinhibited state of 53BP1 in cells[1].

  • CAS Number

    [1648707-79-2]

  • Molecular Formula

    C17H28N2O

  • Molecular Weight

    276.42

  • Smiles

    O=C(C1=CC=CC(C(C)C)=C1)NCCCNC(C)(C)C

  • Target

    MDM-2/p53

  • Purity

    98.15

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0152163-01
5 mgQM-0152163-01
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10 mgQM-0152163-02
10 mgQM-0152163-02
£376.83/ea
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25 mgQM-0152163-03
25 mgQM-0152163-03
£702.46/ea
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£702.46/ea £0.00
50 mgQM-0152163-04
50 mgQM-0152163-04
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UNC3474 [CAS 1648707-79-2]

UNC3474 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.