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SKU:QM-0143888-01
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UNC5293 is a MERTK-selective and potent inhibitor (Ki=190 pM) . UNC5293 inhibits MERTK (IC50=0.9 nM) and is more selective over Axl, Tyro3 and Flt3. UNC5293 exhibits excellent mouse PK properties and is used for bone marrow leukemia research[1].
[2226789-82-6]
C30H42N6O2
518.69
O=C(C1=CC(C)=NC(C)=C1)N2CCC(C3=CN([C@H]4CC[C@H](O)CC4)C5=NC(N[C@@H](C)CCC)=NC=C53)CC2
Anaplastic lymphoma kinase (ALK) ; FLT3; TAM Receptor
Axl; Tyro3
99.93
DMSO : 100 mg/mL (ultrasonic)
4°C (Powder, protect from light)
Room Temperature
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UNC5293 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.