Urantide [CAS 669089-53-6]

Urantide is a selective and competitive urotensin-II (UT) receptor antagonist peptide (pKB=8.3) that blocks human urotensin-II (hU-II) -induced contractions in rat thoracic aorta ex vivo. Urantide can be used to study the (patho) physiological role of hU-II in the mammalian cardiovascular system[1].

[669089-53-6]

C51H66N10O12S2

1075.26

O=C([C@@H](NC([C@H](C(C)(SSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCN)=O)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)C(C)C)=O)C)NC([C@@H](N)CC(O)=O)=O)=O)CC3=CC=CC=C3)N[C@@H]1CC4=CNC5=CC=CC=C45

Others; Urotensin Receptor

10 mM in DMSO

Room temperature