Urease-IN-21

Urease-IN-21 (Compound 11b) is a Urease inhibitor with an IC50 of 0.12 μM. Urease-IN-21 has potent antibacterial activity against helicobacter pylori (H. pylori) and inhibitor activity against P450 enzyme (CYP2C19, CYP2C9, and CYP3A4) . Urease-IN-21 can be used for H. pylori infection research[1].

C25H25N5O3S

475.56

CC1=CC=C(C=C1)S(=O)(N(C2=CC=CC=C2)CC3=CN(CC(NC4=C(C)C=CC=C4)=O)N=N3)=O

Bacterial; Urease

Room temperature