Vadimezan (DMXAA), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities.
CAS Number
[117570-53-3]
Molecular Formula
C17H14O4
Molecular Weight
282.29
Smiles
O=C(O)CC1=CC=CC(C2=O)=C1OC3=C2C=CC(C)=C3C
Target
IFNAR; Influenza Virus; STING
Purity
99.93
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)