Val-Cit-PAB-Exatecan [CAS 2227350-99-2]

Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 and a cathepsin cleavable ADC linker[1].

[2227350-99-2]

C43H49FN8O9

840.9

CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O

Drug-Linker Conjugates for ADC; Topoisomerase

Camptothecins

99.79

DMSO : 100 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice