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Vancomycin prodrug

Vancomycin prodrug

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QM-0010978

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Product Details

  • Description

    Vancomycin prodrug (compound 13c) is a Vancomycin prodrug. Vancomycin prodrug shows antibacterial effect with MICs of 0.78 μM, 0.78 μM, 1.56 μM for S. aureus 330041, MRSA USA 300 and MRSA 3390, respectively. Vancomycin prodrug has the ability to quickly bind to Cys-34 residue of plasma. Vancomycin prodrug exhibits a good therapeutic effect on MRSA USA300 infected mice similar to Vancomycin. Vancomycin prodrug, an albumin-binding acid-sensitive prodrug, effectively reduces Vancomycin’s nephrotoxicity while maintaining its efficacy for Gram-positive bacterial infections[1].

  • Molecular Formula

    C85H95Cl2N11O29

  • Molecular Weight

    1805.63

  • Smiles

    CN[C@@H](C(N[C@H]1C(N[C@H](C(N[C@H]2C(N[C@H]3C(N[C@@H]([C@@H](C4=CC(Cl)=C(OC5=CC2=CC(OC6=CC=C([C@H]1O)C=C6Cl)=C5O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O[C@H]8C[C@](/N=C/C9=CC=C(C=C9O)OCC(NCCCCCCN%10C(C=CC%10=O)=O)=O)([C@@H]([C@@H](O8)C)O)C)O)O)CO)C=C4)O)C(N[C@@H](C%11=CC(O)=CC(O)=C%11C%12=C(C=CC3=C%12)O)C(O)=O)=O)=O)=O)=O)CC(N)=O)=O)=O)CC(C)C

  • Target

    Antibiotic; Autophagy; Bacterial

  • Shipping Conditions

    Room temperature
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1 EachQM-0010978
1 EachQM-0010978
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Vancomycin prodrug

Vancomycin prodrug is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.