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Vandetanib [CAS 443913-73-3]

Vandetanib [CAS 443913-73-3]

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QM-0081902-01

£62.26 GBP
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Product Details

  • Description

    Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM) . Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) [1].

  • CAS Number

    [443913-73-3]

  • Molecular Formula

    C22H24BrFN4O2

  • Molecular Weight

    475.35

  • Smiles

    FC1=CC(Br)=CC=C1NC2=NC=NC3=CC(OCC4CCN(CC4)C)=C(C=C23)OC

  • Target

    Apoptosis; Autophagy; VEGFR

  • Isoform

    VEGFR2/KDR/Flk-1; VEGFR3/Flt-4

  • Purity

    99.95

  • Solubility

    DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0081902-01
5 mgQM-0081902-01
£62.26/ea		 £0.00
£62.26/ea £0.00
10 mgQM-0081902-02
10 mgQM-0081902-02
£89.13/ea		 £0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0081902-03
10 mM - 1 mLQM-0081902-03
£95.88/ea		 £0.00
£95.88/ea £0.00
25 mgQM-0081902-04
25 mgQM-0081902-04
£115.00/ea		 £0.00
£115.00/ea £0.00
50 mgQM-0081902-05
50 mgQM-0081902-05
£215.24/ea		 £0.00
£215.24/ea £0.00
100 mgQM-0081902-06
100 mgQM-0081902-06
£319.73/ea		 £0.00
£319.73/ea £0.00
500 mgQM-0081902-07
500 mgQM-0081902-07
£651.42/ea		 £0.00
£651.42/ea £0.00
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Vandetanib [CAS 443913-73-3]

Vandetanib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.