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Vasculotide (TFA)

Vasculotide (TFA)

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SKU:QM-0198521-01

£226.18 GBP
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  • Description

    Vasculotide TFA, an angiopoietin-1 mimetic, is a Tie-2 activator and induces Tie-2 phosphorylation. Vasculotide has anti-inflammatiory effect and anti-permeability. Vasculotide TFA ameliorates endotoxin-induced endothelial barrier dysfunction. Vasculotide TFA promotes angiogenesis in a mouse model of diabetic ulcer. Vasculotide TFA protects mice from vascular leakage and reduces mortality in murine abdominal sepsis. Vasculotide TFA decreases microvascular leakage and improves microcirculatory perfusion in a rat model of hemorrhagic shock[1][2][3].

  • Smiles

    O=C(CCN1C(CC(SC[C@@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](CC3=CN=CN3)C(N[C@@H](CC4=CN=CN4)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC5=CN=CN5)C(N[C@H](CO)C(N[C@H](C(O)=O)CC6=CC=CC=C6)=O)=O)=O)=O)=O)=O)=O)N)C1=O)=O)NCCOCCOCC(COCCOCCNC(CCN7C(C(SC[C@@H](C(N[C@@H](CC8=CN=CN8)C(N[C@H](CC9=CN=CN9)C(N[C@@H](CC%10=CN=CN%10)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC%11=CN=CN%11)C(N[C@H](CO)C(N[C@H](C(O)=O)CC%12=CC=CC=C%12)=O)=O)=O)=O)=O)=O)=O)N)CC7=O)=O)=O)(COCCOCCNC(CCN%13C(C(SC[C@H](N)C(N[C@@H](CC%14=CN=CN%14)C(N[C@H](CC%15=CN=CN%15)C(N[C@@H](CC%16=CN=CN%16)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC%17=CN=CN%17)C(N[C@H](CO)C(N[C@H](C(O)=O)CC%18=CC=CC=C%18)=O)=O)=O)=O)=O)=O)=O)CC%13=O)=O)=O)COCCOCCNC(CCN%19C(C(SC[C@H](N)C(N[C@@H](CC%20=CN=CN%20)C(N[C@H](CC%21=CN=CN%21)C(N[C@@H](CC%22=CN=CN%22)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC%23=CN=CN%23)C(N[C@H](CO)C(N[C@H](C(O)=O)CC%24=CC=CC=C%24)=O)=O)=O)=O)=O)=O)=O)CC%19=O)=O)=O.O=C(O)C(F)(F)F.[n].[n].[n].[n].[x]

  • Target

    Tie

  • Purity

    99.72

  • Solubility

    DMSO : 25 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)

  • Storage Conditions

    -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Blue Ice

Your cart
Variant Variant total Quantity Price Variant total
1 mgQM-0198521-01
1 mgQM-0198521-01
£226.18/ea
£0.00
£226.18/ea £0.00
5 mgQM-0198521-02
5 mgQM-0198521-02
£501.98/ea
£0.00
£501.98/ea £0.00
10 mgQM-0198521-03
10 mgQM-0198521-03
£777.78/ea
£0.00
£777.78/ea £0.00
25 mgQM-0198521-04
25 mgQM-0198521-04
£1,217.62/ea
£0.00
£1,217.62/ea £0.00

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Vasculotide (TFA)

Vasculotide (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.