VB-85247

VB-85247 is a STING agonist. VB-85247 induces upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as maturation and activation of dendritic cells by activating the STING pathway. VB-85247 can achieve regression of intrabladder tumors and can be used in bladder cancer research[1].

C18H18FN9Na2O8P2S2

679.45

O=C1NC(N)=NC2=C1N=CN2[C@H]3[C@H](OP4(S[Na])=O)[C@H](F)[C@@H](COP(OCCN5C6=C(N=C5CO4)N=CN=C6)(S[Na])=O)O3

CXCR; IFNAR; Interleukin Related; STING; TNF Receptor

Room temperature