VEGF-IN-1

VEGF-IN-1 (compound 6) can reduce the release of VEGF in U87-MG cells and inhibit angiogenesis in vitro. VEGF-IN-1 can inhibit cell proliferation by inducing autophagy in tumor cells, with an IC50 value of 28.35 μM for U87-MG cells[1].

C27H22Cl2N4Ru

574.47

CC(C=C1)=CC=C1C2=NC3=C(N2)C4=C(C5=C3C=CC=[N]5[Ru]6([])Cl)[N]6=CC=C4.Cc7ccccc7.[Cl-]

VEGFR

Room temperature