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Vemurafenib-d5 [CAS 1365986-90-8]
Vemurafenib-d5 [CAS 1365986-90-8]
SKU:QM-0139966-01
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Product Details
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Description
Vemurafenib-d5 is the deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].
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CAS Number
[1365986-90-8]
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Molecular Formula
C23H13D5ClF2N3O3S
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Molecular Weight
494.95
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Smiles
C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CC(C([2H])([2H])[2H])([2H])[2H])(=O)=O)=CC=C4F
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Target
Autophagy; Isotope-Labeled Compounds; Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Vemurafenib-d5 [CAS 1365986-90-8]
Vemurafenib-d5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.