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Vemurafenib-d7 [CAS 1365986-73-7]
Vemurafenib-d7 [CAS 1365986-73-7]
SKU:QM-0139967
£1,330.61 GBP
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Product Details
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Description
Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].
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CAS Number
[1365986-73-7]
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Molecular Formula
C23H11D7ClF2N3O3S
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Molecular Weight
496.97
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Smiles
O=C(C1=C(C(NS(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])(=O)=O)=CC=C1F)F)C2=CNC3=NC=C(C4=CC=C(C=C4)Cl)C=C23
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Target
Autophagy; Isotope-Labeled Compounds; Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Vemurafenib-d7 [CAS 1365986-73-7]
Vemurafenib-d7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.