Veratridine [CAS 71-62-5]

Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow[1][2].

[71-62-5]

C36H51NO11

673.79

C[C@@]12[C@]34[C@](CC[C@]1([H])[C@@](O)([C@@H](OC(C5=CC(OC)=C(OC)C=C5)=O)CC2)O4)([H])[C@@]6(O)[C@](O)([C@@]7([H])[C@@](O)([C@](O)([C@@]8([H])N(C[C@@H](C)CC8)C7)C)[C@@H](O)C6)C3

Sodium Channel

Nav1.7

99.42

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H300, H310, H315, H319, H330, H335, H361

H300, H310, H315, H319, H330, H335, H361