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VGSC blocker-1 [CAS 2230472-55-4]

VGSC blocker-1 [CAS 2230472-55-4]

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SKU:QM-0060780

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  • Description

    VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5) . VGSC blocker-1 blocks INa peak currents 34.9% at 1 μM and inhibits cell invasion 0.3% at 1 μM in human breast cancer cell line MDA-MB-231, without affecting the cell viability[1].

  • CAS Number

    [2230472-55-4]

  • Molecular Formula

    C24H32F2N2

  • Molecular Weight

    386.52

  • Smiles

    FC1=CC=C(C(C2=CC=C(F)C=C2)CCCNCCCN3CCCCC3)C=C1

  • Target

    Sodium Channel

  • Isoform

    Nav1.5

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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VGSC blocker-1 [CAS 2230472-55-4]

VGSC blocker-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.