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VGSC blocker-1 [CAS 2230472-55-4]
VGSC blocker-1 [CAS 2230472-55-4]
SKU:QM-0060780
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Product Details
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Description
VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5) . VGSC blocker-1 blocks INa peak currents 34.9% at 1 μM and inhibits cell invasion 0.3% at 1 μM in human breast cancer cell line MDA-MB-231, without affecting the cell viability[1].
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CAS Number
[2230472-55-4]
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Molecular Formula
C24H32F2N2
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Molecular Weight
386.52
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Smiles
FC1=CC=C(C(C2=CC=C(F)C=C2)CCCNCCCN3CCCCC3)C=C1
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Target
Sodium Channel
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Isoform
Nav1.5
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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VGSC blocker-1 [CAS 2230472-55-4]
VGSC blocker-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.