Vialinin A [CAS 858134-23-3]

Vialinin A (Terrestrin A) is a p-terphenyl compound that can be derived from a Chinese edible mushroom. Vialinin A is an inhibitor of ubiquitin-specific peptidase 4 (USP4) and has anti-inflammatory and antioxidant properties. Vialinin A can alleviate cerebral ischaemia-reperfusion injury-induced neurological deficits and neuronal apoptosis. Vialinin A promotes activation of Keap1-Nrf2-ARE signaling pathway and increases the protein degradation of Keap1. Vialinin A possesses various pharmacological activities in cancer, Kawasaki disease, asthma, and pathological scarring. Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1) . Vialinin A can be studied in reseach for autoimmune diseases, cancer and ischaemic stroke[1][2][3].

[858134-23-3]

C34H26O8

562.57

O=C(CC1=CC=CC=C1)OC2=C(C(C3=CC=C(C=C3)O)=C(C(O)=C2C4=CC=C(O)C=C4)O)OC(CC5=CC=CC=C5)=O

Deubiquitinase; E1/E2/E3 Enzyme; Keap1-Nrf2; TNF Receptor

99.9

DMSO : 100 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture)

Blue Ice