Vilanterol-d12

Vilanterol-d12 (GW642444-d12) is deuterium labeled Vilanterol. Vilanterol (GW642444) is a long-acting β2-adrenoceptor (β2-AR) agonist with 24 h activity. The pEC50s for β2-AR, β1-AR and β3-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.

C24H21D12Cl2NO5

498.5

OC1=CC=C(C=C1CO)[C@H](CNC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])OCCOCC2=C(C=CC=C2Cl)Cl)O

Adrenergic Receptor; Isotope-Labeled Compounds

Room temperature