VinclozolinM2-2204

VinclozolinM2-2204 is a androgen receptor (AR) AUTOTAC degrader, with an DC50 of 200 nM in LNCaP prostate cancer cells. VinclozolinM2-2204 induces the formation of AR+LC3+ autophagic membranes. VinclozolinM2-2204 can be used for the research of cancer[1]. (Pink: AR inhibitor ; Black: linker (HY-128833) ; Blue: CRBN Ligand (HY-168293) )

C43H51Cl2N3O9

824.79

O[C@H](CNCCOCCOCCNC(N(C1=CC(Cl)=CC(Cl)=C1)C(C(C)(O)C=C)=O)=O)COC2=CC(OCCC3=CC=CC=C3)=C(OCCC4=CC=CC=C4)C=C2

Androgen Receptor; AUTOTACs

98

DMSO : ≥ 100 mg/mL

4°C (Powder, protect from light, stored under nitrogen)

Room Temperature