Vincristine-d6 (sulfate)
Vincristine-d6 (sulfate)
SKU:QM-0162774-01
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Product Details
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Description
Vincristine-d6 (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
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Molecular Formula
C46H52D6N4O14S
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Molecular Weight
929.07
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Smiles
CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C4=CC([C@](C5=C6C7=CC=CC=C7N5)(C[C@](C[C@](CC)(O)C8)([H])C[N@@]8CC6)C(OC([2H])([2H])[2H])=O)=C(OC)C=C4N9C=O)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C([2H])([2H])[2H])=O.O=S(O)(O)=O
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Target
Apoptosis; Isotope-Labeled Compounds; Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Vincristine-d6 (sulfate)
Vincristine-d6 (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.