VIR-165 [CAS 943790-62-3]

VIR-165 is a modified form of virus inhibitory peptide (VIRIP) that binds the fusion peptide of the gp41 subunit and prevents its insertion into the target membrane. VIRIP inhibits a wide variety of human immunodeficiency virus type 1 (HIV-1) strains[1].

[943790-62-3]

C109H156N22O25S2

2238.67

O=C1[C@@]2([H])N(CCC2)C([C@](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@]3([H])N1CCC3)=O)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)=O)CC6=CC=CC=C6)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)CC8=CC=CC=C8)=O)NC([C@H]9N(CCC9)C([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)CO)=O)([H])[C@@H](C)CC)=O

HIV

10 mM in DMSO

Room temperature