Vortioxetine-d4

Vortioxetine-d4 (Lu AA 21004-d4) is the deuterium labeled Vortioxetine. Vortioxetine is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM)[2].

C18H18D4N2S

302.47

[2H]C(NC([2H])([2H])C1)([2H])CN1C(C=CC=C2)=C2SC3=CC=C(C)C=C3C

5-HT Receptor; Isotope-Labeled Compounds; Serotonin Transporter

5-HT1 Receptor;5-HT3 Receptor;5-HT7 Receptor

Room temperature