VPC-70619 [CAS 2361742-30-3]

VPC-70619 is a potent N-Myc inhibitor. VPC-70619 blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box and exhibits potent inhibitory activity against N-Myc-dependent cell lines. VPC-70619 can partially reverse paclitaxel resistance in cells by reducing MYCN expression. VPC-70619 can be used for cancer research (e.g., neuroblastoma and thyroid cancer)[2].

[2361742-30-3]

C16H8ClF3N4O

364.71

N#CC1=CC(C(F)(F)F)=C(C=C1)NNC(C2=CC=C(C(Cl)=C2)C#N)=O

C-Myc

99.93

DMSO : ≥ 100 mg/mL

-20°C, 3 years (Powder)

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