Vrucaparib-TP4 [CAS 2410557-03-6]

Vrucaparib-TP4 (Compound 9) is a PARP1 PROTAC-type degrader. Vrucaparib-TP4 promotes the ubiquitination and degradation of PARP1. Vrucaparib-TP4 can be used in the research of tumors[1].

[2410557-03-6]

C58H75FN10O9S

1107.34

O=C1NCCC2=C(NC3=CC(F)=CC1=C32)C4=CC=C(C=C4)CN(CCCCC5=CN(N=N5)CCOCCOCCOCCOCCC(N[C@H](C(N6C[C@@H](C[C@H]6C(NCC7=CC=C(C=C7)C8=C(C)N=CS8)=O)O)=O)C(C)(C)C)=O)C

PARP; PROTACs

PARP1

Room temperature