VU0424465 [CAS 1428630-85-6]

Name: VU0424465 [CAS 1428630-85-6]
Brand: QuantiMol
SKU: QM-0138582-01
Price: 351.32 GBP
Availability: InStock

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SKU:QM-0138582-01

£351.32 GBP

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Product Details

Description
VU0424465 is a potent and partial PAM (positive allosteric modulator) -agonist for mGlu5 mediated iCa2+ mobilization. VU0424465 exhibits high affinity at MPEP allosteric binding site, with a Ki value of 11.8 nM. VU0424465 is also a agonist for pERK1/2 in cortical neurons[1][2].
CAS Number
[1428630-85-6]
Molecular Formula
C19H19FN2O2
Molecular Weight
326.36
Smiles
O=C(N[C@H](C)C(O)(C)C)C1=NC=C(C=C1)C#CC2=CC=CC(F)=C2
Target
MGluR; PERK
Isoform
MGluR5
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0138582-01	5 mgQM-0138582-01 £351.32/ea	£0.00	Quantity	£351.32/ea	£0.00

10 mgQM-0138582-02	10 mgQM-0138582-02 £539.64/ea	£0.00	Quantity	£539.64/ea	£0.00

25 mgQM-0138582-03	25 mgQM-0138582-03 £1,029.29/ea	£0.00	Quantity	£1,029.29/ea	£0.00

50 mgQM-0138582-04	50 mgQM-0138582-04 £1,618.57/ea	£0.00	Quantity	£1,618.57/ea	£0.00

100 mgQM-0138582-05	100 mgQM-0138582-05 £2,560.19/ea	£0.00	Quantity	£2,560.19/ea	£0.00

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VU0424465 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.