VU0463841 [CAS 1439095-16-5]

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SKU:QM-0133709

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Description
VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research[1].
CAS Number
[1439095-16-5]
Molecular Formula
C13H8ClFN4O
Molecular Weight
290.68
Smiles
O=C(NC1=NC=C(C=C1)Cl)NC2=CC(F)=CC(C#N)=C2
Target
MGluR
Isoform
MGluR5
Shipping Conditions
Room temperature

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VU0463841 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.