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SKU:QM-0136223-01
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VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].
[1809085-30-0]
C18H15ClFN5O2
387.8
ClC1=CN=C(OCC2=NN([C@H](C)CN(C3=C(F)N=CC=C3)C4=O)C4=C2)C=C1
MGluR
MGluR3
10mM
99.55
DMSO : 250 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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VU0650786 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.