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VU439

VU439

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SKU:QM-0012413

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  • Description

    VU439 is a functionalized photoaffinity ligand of Elexacaftor. VU439 retains the activity of Elexacaftor as a CFTR corrector and can identify SCCPDH as a specific off-target of Elexacaftor through chemoproteomics[1].

  • Molecular Formula

    C32H40F3N9O4S

  • Molecular Weight

    703.78

  • Smiles

    C#CCCC1(N=N1)CCN2N=C(C)C(S(=O)(NC(C3=CC=C(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)N=C3N5C[C@@H](C)CC5(C)C)=O)=O)=C2

  • Target

    CFTR

  • Shipping Conditions

    Room temperature

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VU439

VU439 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.