WAY-181187 (oxalate) [CAS 1883548-85-3]

WAY-181187 (SAX-187) oxalate is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM. WAY-181187 oxalate mediates 5-HT6 receptor-dependent signal pathways, such as cAMP, Fyn and ERK1/2 kinase, as specific agonist[1][2].

[1883548-85-3]

C17H15ClN4O6S2

470.91

O=C(C(O)=O)O.O=S(C1=C(N=C2SC=CN21)Cl)(N3C=C(CCN)C4=C3C=CC=C4)=O

5-HT Receptor

5-HT6 Receptor; MUC2

10 mM in DMSO

Room temperature