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SKU:QM-0149883-01
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WDR5-0102 is an inhibitor targeting WDR5-MLL1 interface (Kdis=7 μM, Kd=4 μM) . WDR5-0102 suppresses MLL1 HMT activity, but not human H3K4 methyltransferase SETD7 and six other HMTs: G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5[1][2].
[824960-50-1]
C18H19ClN4O3
374.82
O=C(C1=C(Cl)C=CC=C1)NC2=CC([N+]([O-])=O)=CC=C2N3CCN(CC3)C
WDR5
97.07
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
4°C (Powder, protect from light)
Room Temperature
H302, H315, H319
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WDR5-0102 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.