WHN-88 [CAS 2490686-86-5]

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SKU:QM-0124753

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Product Details

Description
WHN-88 is a Porcupine (PORCN) inhibitor. WHN-88 can eliminate the palmitoylation of Wnt ligands, preventing their secretion and subsequent Wnt/β-catenin signaling. WHN-88 can inhibit cancer cell stemness and suppress the occurrence and development of breast tumors in MMTV-Wnt1 transgenic mice[1].
CAS Number
[2490686-86-5]
Molecular Formula
C18H13I2N3O2
Molecular Weight
557.12
Smiles
O=C(CN1C=C(I)C(C(I)=C1)=O)NC2=NC=C(C3=CC=CC=C3)C=C2
Target
Porcupine; Wnt; β-catenin
Shipping Conditions
Room temperature

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WHN-88 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.