WP-1034 [CAS 857064-42-7]

WP-1034 is a JAK-STAT inhibitor with proapoptotic and antileukemic activity in acute myeloid leukemia (AML) . WP-1034 blocks activation of Stat 3 and 5. WP-1034 induces cell cycle arrest and triggers apoptosis. WP-1034 can be used for AML research[1].

[857064-42-7]

C18H15N3O3

321.33

O=C(N[C@@H](C1=CC=CC=C1)C)/C(C#N)=C/C2=CC=C([N+]([O-])=O)C=C2

Apoptosis; Caspase; JAK; PARP; STAT

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