WS-384 [CAS 2247544-03-0]

WS-384 is a dual LSD1 and DCN1-UBC12 protein-protein interaction inhibitor with oral activity, with IC50 values of 338.79 nM and 14.81 nM, respectively. WS-384 possesses anticancer activity and can cause cell cycle arrest, DNA damage, and induce apoptosis. WS-384 can be used in the research of non-small cell lung cancer (NSCLC) [1].

[2247544-03-0]

C18H21BrClN9S2

542.91

BrC1=CC=C(CSC2=NN3C(SC4=NN=NN4CCN(C)C)=CC(C)=NC3=N2)C=C1.Cl

Apoptosis; Caspase; DNA/RNA Synthesis; E1/E2/E3 Enzyme; Histone Demethylase

98.23

DMSO : 17.86 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, sealed storage, away from moisture)

Room Temperature