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WYE-354 [CAS 1062169-56-5]

WYE-354 [CAS 1062169-56-5]

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QM-0139885-01

£89.13 GBP
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Product Details

  • Description

    WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro[3].

  • CAS Number

    [1062169-56-5]

  • Molecular Formula

    C24H29N7O5

  • Molecular Weight

    495.53

  • Smiles

    COC(NC1=CC=C(C=C1)C2=NC3=C(C(N4CCOCC4)=N2)C=NN3C5CCN(CC5)C(OC)=O)=O

  • Target

    Apoptosis; Autophagy; mTOR

  • Isoform

    MTOR; mTORC1; mTORC2

  • Purity

    98.03

  • Solubility

    DMSO : 6.67 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0139885-01
5 mgQM-0139885-01
£89.13/ea		 £0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0139885-02
10 mM - 1 mLQM-0139885-02
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mgQM-0139885-03
10 mgQM-0139885-03
£139.75/ea		 £0.00
£139.75/ea £0.00
25 mgQM-0139885-04
25 mgQM-0139885-04
£312.44/ea		 £0.00
£312.44/ea £0.00
50 mgQM-0139885-05
50 mgQM-0139885-05
£546.93/ea		 £0.00
£546.93/ea £0.00
100 mgQM-0139885-06
100 mgQM-0139885-06
£740.12/ea		 £0.00
£740.12/ea £0.00
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WYE-354 [CAS 1062169-56-5]

WYE-354 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.