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X-376 [CAS 1365267-27-1]

X-376 [CAS 1365267-27-1]

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QM-0153914-01

£89.13 GBP
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Product Details

  • Description

    X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM) . X-376 is a less potent inhibitor of MET (IC50=0.69 nM) . X-376 displays potent anti-tumor activity[1].

  • CAS Number

    [1365267-27-1]

  • Molecular Formula

    C25H25Cl2FN6O3

  • Molecular Weight

    547.41

  • Smiles

    O=C(C1=NN=C(N)C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1)NC3=CC=C(C(N4CCN(C)CC4)=O)C=C3

  • Target

    Anaplastic lymphoma kinase (ALK) ; c-Met/HGFR

  • Purity

    98.1

  • Solubility

    DMSO : ≥ 37 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302

  • Precautions

    H302
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Variant Variant total Quantity Price Variant total
2 mgQM-0153914-01
2 mgQM-0153914-01
£89.13/ea		 £0.00
£89.13/ea £0.00
5 mgQM-0153914-02
5 mgQM-0153914-02
£188.51/ea		 £0.00
£188.51/ea £0.00
10 mM - 1 mLQM-0153914-03
10 mM - 1 mLQM-0153914-03
£215.24/ea		 £0.00
£215.24/ea £0.00
10 mgQM-0153914-04
10 mgQM-0153914-04
£238.32/ea		 £0.00
£238.32/ea £0.00
25 mgQM-0153914-05
25 mgQM-0153914-05
£464.31/ea		 £0.00
£464.31/ea £0.00
50 mgQM-0153914-06
50 mgQM-0153914-06
£740.12/ea		 £0.00
£740.12/ea £0.00
100 mgQM-0153914-07
100 mgQM-0153914-07
£991.63/ea		 £0.00
£991.63/ea £0.00
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X-376 [CAS 1365267-27-1]

X-376 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.