Xanthone [CAS 90-47-1]

Xanthone is a monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.84 µM. Xanthon inhibits Norepinephrine and high-K+-induced vasoconstriction with IC50 values of 60.26 μM and 82.9 μM, respectively. Xanthon increases intracellular cyclic adenosine 3′,5′-monophosphate (cAMP) content and blocks Ca2+ channels. Xanthone is the scaffold of several pharmacologically active compounds[1][2].

[90-47-1]

C13H8O2

196.21

O=C1C2=C(OC3=C1C=CC=C3)C=CC=C2

Calcium Channel; Monoamine Oxidase

MAO-A

10mM

99.97

DMSO : 10 mg/mL (ultrasonic)

Store at room temperature 3 years

Room Temperature

H410

H410